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Melanocortin-3 receptor regulates the normal fasting response

The melanocortin-3 receptor–deficient (MC3-R(−/−)) mouse exhibits mild obesity without hyperphagia or hypometabolism. MC3-R deletion is reported to increase adiposity, reduce lean mass and white adipose tissue inflammation, and increase sensitivity to salt-induced hypertension. We show here that the...

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Autors principals: Renquist, Benjamin J., Murphy, Jonathan G., Larson, Emily A., Olsen, Dawn, Klein, Robert F., Ellacott, Kate L. J., Cone, Roger D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384161/
https://ncbi.nlm.nih.gov/pubmed/22573815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201994109
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