Evidence for a cytoplasmic microprocessor of pri-miRNAs

microRNAs (miRNAs) represent a class of noncoding RNAs that fine-tune gene expression through post-transcriptional silencing. While miRNA biogenesis occurs in a stepwise fashion, initiated by the nuclear microprocessor, rare noncanonical miRNAs have also been identified. Here we characterize the mol...

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Bibliographic Details
Main Authors: Shapiro, Jillian S., Langlois, Ryan A., Pham, Alissa M., tenOever, Benjamin R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383965/
https://ncbi.nlm.nih.gov/pubmed/22635403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032268.112
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