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Hybrids of a Genetically Engineered Antibody and a Carbon Nanotube Transistor for Detection of Prostate Cancer Biomarkers

We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate cancer, by attaching a genetically engineered single chain variable fragment (scFv) protein with high binding affinity for OPN to a carbon nanotube field-effect transistor (NTFET). Chemical functionalization us...

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Main Authors: Lerner, Mitchell B., D’Souza, Jimson, Pazina, Tatiana, Dailey, Jennifer, Goldsmith, Brett R., Robinson, Matthew K., Johnson, A.T. Charlie
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383883/
https://ncbi.nlm.nih.gov/pubmed/22575126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn300819s
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