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A Tandem Olefin Migration and Prins Cyclization Using Cu(OTf)(2)-Bisphosphine Complexes: An Improved Synthesis of Functionalized Tetrahydropyrans

In situ-generated (bis-DPPMB)-Cu(OTf)(2) complex has been examined to catalyze a tandem olefin migration and Prins cyclization of an alkenol with various aldehydes. The reaction proceeded with electron-rich aromatic aldehydes at room temperature and provided functionalized tetrahydropyrans in good y...

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Detalhes bibliográficos
Main Authors: Ghosh, Arun K., Nicponski, Daniel R., Kass, Jorden
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383828/
https://ncbi.nlm.nih.gov/pubmed/22753996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.04.006
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