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Hyperpolarization-activated cation current I(h) of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy

The hyperpolarization-activated cation current I(h) is an important regulator of neuronal excitability and may contribute to the properties of the dentate gyrus granule (DGG) cells, which constitute the input site of the canonical hippocampal circuit. Here, we investigated changes in I(h) in DGG cel...

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Detalhes bibliográficos
Main Authors: Surges, Rainer, Kukley, Maria, Brewster, Amy, Rüschenschmidt, Christiane, Schramm, Johannes, Baram, Tallie Z., Beck, Heinz, Dietrich, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383809/
https://ncbi.nlm.nih.gov/pubmed/22405820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.02.133
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