Selectively Guanidinylated Aminoglycosides as Antibiotics

The emergence of virulent, drug-resistant bacterial strains coupled with a minimal output of new pharmaceutical agents to combat them makes this a critical time for antibacterial research. Aminoglycosides are a well-studied, highly potent class of naturally occurring antibiotics with scaffolds amena...

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Bibliographic Details
Main Authors: Fair, Richard J., Hensler, Mary E., Thienphrapa, Wdee, Dam, Quang N., Nizet, Victor, Tor, Yitzhak
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383777/
https://ncbi.nlm.nih.gov/pubmed/22639134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200150
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