Bronchoalveolar Lavage Enzyme-Linked Immunospot for Diagnosis of Smear-Negative Tuberculosis in HIV-Infected Patients

BACKGROUND: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been reported to improve the accuracy of TB diagnosis. METHODS: We enrolled HIV-inf...

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Autores principales: Cattamanchi, Adithya, Ssewenyana, Isaac, Nabatanzi, Rose, Miller, Cecily R., Den Boon, Saskia, Davis, J. Lucian, Andama, Alfred, Worodria, William, Yoo, Samuel D., Cao, Huyen, Huang, Laurence
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383728/
https://ncbi.nlm.nih.gov/pubmed/22745833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039838
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