MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer

The identification of new biomarkers for preneoplastic pancreatic lesions (PanINs, IPMNs) and early pancreatic ductal adenocarcinoma (PDAC) is crucial due to the diseasés high mortality rate upon late detection. To address this task we used the novel technique of matrix-assisted laser desorption/ion...

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Detalhes bibliográficos
Main Authors: Grüner, Barbara M., Hahne, Hannes, Mazur, Pawel K., Trajkovic-Arsic, Marija, Maier, Stefan, Esposito, Irene, Kalideris, Evdokia, Michalski, Christoph W., Kleeff, Jörg, Rauser, Sandra, Schmid, Roland M., Küster, Bernhard, Walch, Axel, Siveke, Jens T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383687/
https://ncbi.nlm.nih.gov/pubmed/22761793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039424
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