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MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer

The identification of new biomarkers for preneoplastic pancreatic lesions (PanINs, IPMNs) and early pancreatic ductal adenocarcinoma (PDAC) is crucial due to the diseasés high mortality rate upon late detection. To address this task we used the novel technique of matrix-assisted laser desorption/ion...

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Hlavní autoři: Grüner, Barbara M., Hahne, Hannes, Mazur, Pawel K., Trajkovic-Arsic, Marija, Maier, Stefan, Esposito, Irene, Kalideris, Evdokia, Michalski, Christoph W., Kleeff, Jörg, Rauser, Sandra, Schmid, Roland M., Küster, Bernhard, Walch, Axel, Siveke, Jens T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383687/
https://ncbi.nlm.nih.gov/pubmed/22761793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039424
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