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Proteasome inhibitors and bone disease
Bone disease in patients with multiple myeloma (MM) is characterized by increase in the numbers and activity of bone-resorpting osteoclasts and decrease in the number and function of bone-formation osteoblasts. MM-triggered inhibition of bone formation may stem from suppression of Wnt/β-catenin sign...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383607/ https://ncbi.nlm.nih.gov/pubmed/22726547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2012.04.011 |
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