High Expression of Folate Receptor Alpha in Lung Cancer Correlates with Adenocarcinoma Histology and EGFR Mutation

INTRODUCTION: Folate receptor alpha (FRα) and reduced folate carrier-1 (RFC1) regulate uptake of folate molecules inside the cell. FRα is a potential biomarker of tumors response to antifolate chemotherapy and a target for therapy using humanized monocloncal antibody. Information on the protein expr...

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Main Authors: Nunez, Maria Ines, Behrens, Carmen, Woods, Denise M., Lin, Heather, Suraokar, Milind, Kadara, Humam, Hofstetter, Wayne, Kalhor, Neda, Lee, J. Jack, Franklin, Wilbur, Stewart, David J., Wistuba, Ignacio I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383601/
https://ncbi.nlm.nih.gov/pubmed/22729036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31824de09c
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