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The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing

Nesprin-2, a type II transmembrane protein of the nuclear envelope, is a component of the LINC complex that connects the nuclear lamina with the actin cytoskeleton. To elucidate its physiological role we studied wound healing in Nesprin-2 Giant deficient mice and found that a loss of the protein aff...

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Autors principals: Rashmi, R.N., Eckes, Beate, Glöckner, Gernot, Groth, Marco, Neumann, Sascha, Gloy, Joachim, Sellin, Lorenz, Walz, Gerd, Schneider, Maria, Karakesisoglou, Iakowos, Eichinger, Ludwig, Noegel, Angelika A.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383573/
https://ncbi.nlm.nih.gov/pubmed/22198684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.19090
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