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Apremilast: A Novel PDE4 Inhibitor in the Treatment of Autoimmune and Inflammatory Diseases

Phosphodiesterase 4 (PDE4) is a key enzyme in the degradation of cyclic adenosine monophosphate and is centrally involved in the cytokine production of inflammatory cells, angiogenesis, and the functional properties of other cell types such as keratinocytes. In this review article, apremilast, a nov...

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Detalhes bibliográficos
Main Authors: Schett, Georg, Sloan, Victor S., Stevens, Randall M., Schafer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383510/
https://ncbi.nlm.nih.gov/pubmed/22870453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X10381432
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