Brain metabolite alterations and cognitive dysfunction in early Huntington’s Disease

BACKGROUND: Huntington’s Disease (HD) is a neurodegenerative disorder characterized by early cognitive decline, which progresses at later stages to dementia and severe movement disorder. HD is caused by a cytosine-adenine-guanine triplet-repeat expansion mutation in the Huntingtin gene, allowing ear...

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Detalhes bibliográficos
Main Authors: Unschuld, Paul G., Edden, Richard A. E., Carass, Aaron, Liu, Xinyang, Shanahan, Megan, Wang, Xin, Oishi, Kenichi, Brandt, Jason, Bassett, Susan S., Redgrave, Graham W., Margolis, Russell L., van Zijl, Peter C. M., Barker, Peter B., Ross, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383395/
https://ncbi.nlm.nih.gov/pubmed/22649062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25010
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