Cisplatin-loaded core cross-linked micelles: comparative pharmacokinetics, antitumor activity, and toxicity in mice

Polymer micelles with cross-linked ionic cores are shown here to improve the therapeutic performance of the platinum-containing anticancer compound cisplatin. Biodistribution, antitumor efficacy, and toxicity of cisplatin-loaded core cross-linked micelles of poly(ethylene glycol)-b-poly(methacrylic...

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Detalhes bibliográficos
Main Authors: Oberoi, Hardeep S, Nukolova, Natalia V, Laquer, Frederic C, Poluektova, Larisa Y, Huang, Jiangeng, Alnouti, Yazen, Yokohira, Masanao, Arnold, Lora L, Kabanov, Alexander V, Cohen, Samuel M, Bronich, Tatiana K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383348/
https://ncbi.nlm.nih.gov/pubmed/22745537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29145
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