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Targeted approaches in the treatment of osteoporosis: differential mechanism of action of denosumab and clinical utility

Denosumab is a breakthrough biological drug approved by the Food and Drug Administration and European Medicines Agency for the treatment of osteoporosis in 2010. It is a fully human monoclonal antireceptor activator of nuclear factor kappa-B ligand antibody, which inhibits the activity of osteoclast...

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Bibliografske podrobnosti
Main Authors: Cavalli, Loredana, Brandi, Maria Luisa
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383338/
https://ncbi.nlm.nih.gov/pubmed/22745560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S7688
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