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PlexinA2 Limits Recovery from Corticospinal Axotomy by Mediating Oligodendrocyte-Derived Sema6A Growth Inhibition

Axonal growth from both intact and severed fibers is limited after adult mammalian CNS injury. Myelin proteins contribute to inhibition of axonal growth. Semaphorin6A protein inhibits the extension of developing axons and is highly expressed in adult oligodendrocytes. This expression pattern suggest...

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Detalhes bibliográficos
Main Authors: Shim, Sang-Ohk, Cafferty, William B. J., Schmidt, Eric C., Kim, Byung G., Fujisawa, Hajime, Strittmatter, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383336/
https://ncbi.nlm.nih.gov/pubmed/22564823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.04.007
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