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CpG islands and HTF islands in the HLA class I region: investigation of the methylation status of class I genes leads to precise physical mapping of the HLA-B and -C genes.

We have investigated the accessibility of the 5' CpG rich sequences (CpG islands) present in the 5' region of most if not all HLA class I genes to methylation sensitive rare cutter enzymes. We show that for HLA-A, -B, -C genes and a few other (but not all) class I sequences these CpG islan...

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Bibliografske podrobnosti
Main Authors: Pontarotti, P, Chimini, G, Nguyen, C, Boretto, J, Jordan, B R
Format: Artigo
Jezik:Inglês
Izdano: 1988
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC338331/
https://ncbi.nlm.nih.gov/pubmed/2841643
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