Renoprotective Action of a Matrix Metalloproteinase Inhibitor in Progressive Mesangioproliferative Nephritis

BACKGROUND/AIM: Matrix metalloproteinases (MMPs) play pivotal roles in extracellular matrix turnover and are involved in chronic kidney disease. The renoprotective action of a synthetic MMP inhibitor, compound A, was investigated in chronic nephritis. METHODS: Nephritis was induced by a single injec...

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Bibliographische Detailangaben
Hauptverfasser: Kuroda, Takayuki, Masui, Masao, Notoya, Mitsuru, Ito, Masashi, Tamura, Yoshinori, Okamoto, Hiroyuki, Kanaoka, Eri, Shinosaki, Toshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2012
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383302/
https://ncbi.nlm.nih.gov/pubmed/22739248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000338801
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