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Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2

Wnt signaling is initiated upon binding of Wnt proteins to Frizzled proteins and their co-receptors LRP5 and 6. The signal is then propagated to several downstream effectors, mediated by the phosphoprotein scaffold, dishevelled. We report a novel role for arginine methylation in regulating Wnt3a-sti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bikkavilli, Rama Kamesh, Malbon, Craig C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383259/
https://ncbi.nlm.nih.gov/pubmed/22357953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.100933
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