Method Development and Validation of Almotriptan in Human Plasma by HPLC Tandem Mass Spectrometry: Application to Pharmacokinetic Study

A simple, sensitive and selective method has been developed for quantification of Almotriptan (AL) in human plasma using Almotriptan-d(6) (ALD6) as an internal standard. Almotriptan and Almotriptan-d(6) were detected with proton adducts at m/z 336.1→201.1 and 342.2→207.2 in multiple reaction monitor...

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Hlavní autoři: Ravikumar, Konda, Chandu, Babu Rao, Challa, Balasekhara Reddy, Chandrasekhar, Kottapalli B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Österreichische Apotheker-Verlagsgesellschaft 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383208/
https://ncbi.nlm.nih.gov/pubmed/22896823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1112-01
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