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The helical repeat of underwound DNA in solution.

Closed circular DNA was relaxed with a topoisomerase in the presence of varying concentrations of the intercalating dye, ethidium bromide, to create underwound, planar DNA rings. We directly determined the helical repeat of these DNA molecules by the Gaussian center method and found that it varied a...

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Bibliografiske detaljer
Main Authors: Richardson, S M, Boles, T C, Cozzarelli, N R
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC338317/
https://ncbi.nlm.nih.gov/pubmed/3399409
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