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The Absolute Free Energy of Binding of Avidin/Biotin Revisited

The binding of biotin to avidin is one of the strongest in nature with absolute free energy of binding, ΔA(0) = −20.4 kcal/mol. Therefore, this complex became a target for a large number of computational studies, which all, however, are based on approximate techniques or simplified models and have l...

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Autors principals: General, Ignacio J., Dragomirova, Ralitsa, Meirovitch, Hagai
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383089/
https://ncbi.nlm.nih.gov/pubmed/22300239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp212276m
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