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LINC Complexes Form by Binding of Three KASH Peptides to the Interfaces of Trimeric SUN proteins

Linker of Nucleoskeleton and Cytoskeleton (LINC) complexes span the nuclear envelope and are composed of KASH and SUN proteins residing in the outer and inner nuclear membrane, respectively. LINC formation relies on direct binding of KASH and SUN in the perinuclear space. Thereby, molecular tethers...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sosa, Brian A., Rothballer, Andrea, Kutay, Ulrike, Schwartz, Thomas U
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383001/
https://ncbi.nlm.nih.gov/pubmed/22632968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.046
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