Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation

A key feature differentiating nonpathogenic SIV infection of sooty mangabeys (SMs) from pathogenic HIV/SIV infections is the rapid resolution of type I IFN (IFN-I) responses and IFN-stimulated gene expression during the acute-to-chronic phase transition and the establishment of an immune quiescent s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vanderford, Thomas H., Slichter, Chloe, Rogers, Kenneth A., Lawson, Benton O., Obaede, Rend, Else, James, Villinger, Francois, Bosinger, Steven E., Silvestri, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2012
Pynciau:
Immunobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382934/
https://ncbi.nlm.nih.gov/pubmed/22550346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-411496
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