Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients

Lymphopenia (< 1Giga/L) detected before initiation of chemotherapy is a predictive factor for death in metastatic solid tumors. Combinatorial T cell repertoire (TCR) diversity was investigated and tested either alone or in combination with lymphopenia as a prognostic factor at diagnosis for overa...

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Autors principals: Manuel, Manuarii, Tredan, Olivier, Bachelot, Thomas, Clapisson, Gilles, Courtier, Anais, Parmentier, Gilles, Rabeony, Tioka, Grives, Audrey, Perez, Solène, Mouret, Jean-François, Perol, David, Chabaud, Sylvie, Ray-Coquard, Isabelle, Labidi-Galy, Intidhar, Heudel, Pierre, Pierga, Jean-Yves, Caux, Christophe, Blay, Jean-Yves, Pasqual, Nicolas, Ménétrier-Caux, Christine
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382902/
https://ncbi.nlm.nih.gov/pubmed/22754761
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