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A novel mechanism for cancer cells to evade immune attack by NK cells: The interaction between NKp44 and proliferating cell nuclear antigen

We recently reported proliferating cell nuclear antigen (PCNA) as a ligand for the NK cell activating receptor, NKp44, which unexpectedly triggers inhibition. The recognition of nuclear proteins such as PCNA, by related NK cell receptors has been reported. Widespread upregulation of PCNA in tumor ce...

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Detalhes bibliográficos
Main Authors: Rosental, Benyamin, Hadad, Uzi, Brusilovsky, Michael, Campbell, Kerry S., Porgador, Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382898/
https://ncbi.nlm.nih.gov/pubmed/22754791
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