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Targeting cancer stem cells with ALDH1A1-based immunotherapy

ALDH(bright) cells in human tumor cells lines, xenografts and lesions have been shown to have characteristics of cancer stem cells (CSC). We have shown that these cells are recognized by ALDH1A1-specific CD8(+) T cells in vitro and in vivo. The results support the potential of ALDH1A1-based immunoth...

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書目詳細資料
主要作者: DeLeo, Albert B.
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382868/
https://ncbi.nlm.nih.gov/pubmed/22737624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.18826
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