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Smoothing T cell roads to the tumor: Chemokine post-translational regulation
We described a novel tumor-associated immunosuppressive mechanism based on post-translational modifications of chemokines by reactive nitrogen species (RNS). To overcome tumor immunosuppressive hindrances, we designed and developed a new drug, AT38, that inhibits RNS generation at the tumor site. Co...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382857/ https://ncbi.nlm.nih.gov/pubmed/22737626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19069 |
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