Muscarinic Type 3 Receptor Induces Cytoprotective Signaling in Salivary Gland Cells through Epidermal Growth Factor Receptor Transactivation

Muscarinic type 3 receptor (M3R) plays a pivotal role in the induction of glandular fluid secretions. Although M3R is often the target of autoantibodies in Sjögren's syndrome (SjS), chemical agonists for M3R are clinically used to stimulate saliva secretion in patients with SjS. Aside from its...

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Autors principals: Kajiya, Mikihito, Ichimonji, Isao, Min, Christine, Zhu, Tongbo, Jin, Jun-O, Yu, Qing, Almazrooa, Soulafa A., Cha, Seunghee, Kawai, Toshihisa
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382834/
https://ncbi.nlm.nih.gov/pubmed/22511543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.077354
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