Muscarinic Type 3 Receptor Induces Cytoprotective Signaling in Salivary Gland Cells through Epidermal Growth Factor Receptor Transactivation

Muscarinic type 3 receptor (M3R) plays a pivotal role in the induction of glandular fluid secretions. Although M3R is often the target of autoantibodies in Sjögren's syndrome (SjS), chemical agonists for M3R are clinically used to stimulate saliva secretion in patients with SjS. Aside from its...

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Главные авторы: Kajiya, Mikihito, Ichimonji, Isao, Min, Christine, Zhu, Tongbo, Jin, Jun-O, Yu, Qing, Almazrooa, Soulafa A., Cha, Seunghee, Kawai, Toshihisa
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382834/
https://ncbi.nlm.nih.gov/pubmed/22511543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.077354
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