Anti-Proliferation and Anti-Invasion Effects of Diosgenin on Gastric Cancer BGC-823 Cells with HIF-1α shRNAs

Drug resistance is a major factor for the limited efficacy of chemotherapy in gastric cancer treatment. Hypoxia-inducible factor-1α (HIF-1α), a central transcriptional factor in hypoxia, is suggested to participate in the resistance. Here, we identified a hypoxia-mimic (cobalt chloride) sensitive ga...

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Huvudupphovsmän: Mao, Zhu-Jun, Tang, Qian-Jue, Zhang, Ci-An, Qin, Zhi-Feng, Pang, Bin, Wei, Pin-kang, Liu, Bo, Chou, Yuan-Neng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Molecular Diversity Preservation International (MDPI) 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382793/
https://ncbi.nlm.nih.gov/pubmed/22754381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13056521
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