Inhibition of airway remodeling in IL-5–deficient mice

To determine the role of IL-5 in airway remodeling, IL-5–deficient and WT mice were sensitized to OVA and challenged by repetitive administration of OVA for 3 months. IL-5–deficient mice had significantly less peribronchial fibrosis (total lung collagen content, peribronchial collagens III and V) an...

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Detalhes bibliográficos
Main Authors: Cho, Jae Youn, Miller, Marina, Baek, Kwang Je, Han, Ji Won, Nayar, Jyothi, Lee, Sook Young, McElwain, Kirsti, McElwain, Shauna, Friedman, Stephanie, Broide, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC338264/
https://ncbi.nlm.nih.gov/pubmed/14966564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419133
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