Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

Inorganic phosphate is essential for ECM mineralization and also as a constituent of important molecules in cellular metabolism. Investigations of several hypophosphatemic diseases indicated that a hormone-like molecule probably regulates serum phosphate concentration. FGF23 has recently been recogn...

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Main Authors: Shimada, Takashi, Kakitani, Makoto, Yamazaki, Yuji, Hasegawa, Hisashi, Takeuchi, Yasuhiro, Fujita, Toshiro, Fukumoto, Seiji, Tomizuka, Kazuma, Yamashita, Takeyoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC338262/
https://ncbi.nlm.nih.gov/pubmed/14966565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419081
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