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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Impairs G2 Checkpoint in Human Nasopharyngeal Epithelial Cells through Defective Chk1 Activation

Nasopharyngeal carcinoma (NPC) is a common cancer in Southeast Asia, particularly in southern regions of China. EBV infection is closely associated with NPC and has long been postulated to play an etiological role in the development of NPC. However, the role of EBV in malignant transformation of nas...

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Hlavní autoři: Deng, Wen, Pang, Pei Shin, Tsang, Chi Man, Hau, Pok Man, Yip, Yim Ling, Cheung, Annie L. M., Tsao, Sai Wah
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382577/
https://ncbi.nlm.nih.gov/pubmed/22761726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039095
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