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Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission

The hexameric protein p97, a very abundant type II AAA ATPase (ATPase associated with various cellular activities), is involved in a diverse range of cellular functions. During its ATPase cycle p97 functions as an ATP motor, converting the chemical energy released upon hydrolysis of ATP to ADP into...

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Autors principals: Huang, Chengdong, Li, Guangtao, Lennarz, William J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382474/
https://ncbi.nlm.nih.gov/pubmed/22675116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205853109
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