Phospholipogenic Pharmaceuticals Are Associated with a Higher Incidence of Histological Findings than Nonphospholipogenic Pharmaceuticals in Preclinical Toxicology Studies

While phospholipidosis is thought to be an adaptive response to chemical challenge, many phospholipogenic compounds are known to display adverse effects in preclinical species and humans. To investigate the link between phospholipogenic administration and incidence of preclinical histological signal...

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Detalhes bibliográficos
Main Authors: Barone, Linda R., Boyer, Scott, Damewood, James R., Fikes, James, Ciaccio, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382391/
https://ncbi.nlm.nih.gov/pubmed/22745636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/308594
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