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G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function

G protein-coupled receptors (GPCRs) play key physiological roles in numerous tissues, including the heart, and their dysfunction influences a wide range of cardiovascular diseases. Recently, the notion of nuclear localization and action of GPCRs has become more widely accepted. Nuclear-localized rec...

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Detalhes bibliográficos
Main Authors: Tadevosyan, Artavazd, Vaniotis, George, Allen, Bruce G, Hébert, Terence E, Nattel, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382322/
https://ncbi.nlm.nih.gov/pubmed/22183719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.222794
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