Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies

Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Usin...

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Detalhes bibliográficos
Main Authors: Frazer, J. Kimble, Batchelor, Lance A., Bradley, Diana F., Brown, Kim H., Dobrinski, Kimberly P., Lee, Charles, Trede, Nikolaus S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382231/
https://ncbi.nlm.nih.gov/pubmed/22745640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/627920
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