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Fluorescence-Based Phenotypic Selection Allows Forward Genetic Screens in Haploid Human Cells

The isolation of haploid cell lines has recently allowed the power of forward genetic screens to be applied to mammalian cells. The interest in applying this powerful genetic approach to a mammalian system is only tempered by the limited utility of these screens, if confined to lethal phenotypes. He...

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Detalhes bibliográficos
Main Authors: Duncan, Lidia M., Timms, Richard T., Zavodszky, Eszter, Cano, Florencia, Dougan, Gordon, Randow, Felix, Lehner, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382162/
https://ncbi.nlm.nih.gov/pubmed/22745803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039651
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