Astragaloside IV, a Novel Antioxidant, Prevents Glucose-Induced Podocyte Apoptosis In Vitro and In Vivo

Glucose-induced reactive oxygen species (ROS) production initiates podocyte apoptosis, which represents a novel early mechanism leading to diabetic nephropathy (DN). Here, we tested the hypothesis that Astragaloside IV(AS-IV) exerts antioxidant and antiapoptotic effects on podocytes under diabetic c...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gui, Dingkun, Guo, Yongping, Wang, Feng, Liu, Wei, Chen, Jianguo, Chen, Yifang, Huang, Jianhua, Wang, Niansong
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382154/
https://ncbi.nlm.nih.gov/pubmed/22745830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039824
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