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Vascular Endothelial Growth Factor Receptor-3 Directly Interacts with Phosphatidylinositol 3-Kinase to Regulate Lymphangiogenesis

BACKGROUND: Dysfunctional lymphatic vessel formation has been implicated in a number of pathological conditions including cancer metastasis, lymphedema, and impaired wound healing. The vascular endothelial growth factor (VEGF) family is a major regulator of lymphatic endothelial cell (LEC) function...

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Detalhes bibliográficos
Main Authors: Coso, Sanja, Zeng, Yiping, Opeskin, Kenneth, Williams, Elizabeth D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382126/
https://ncbi.nlm.nih.gov/pubmed/22745786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039558
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