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Modification of T cell receptor beta chain gene: the J2 region but not the J1 region of the T cell receptor beta chain gene is hypomethylated in human B cells and monocytes.

In order to determine the relationship between the generation of a 1.0 kb mRNA and methylation of the T cell receptor beta chain gene, we have analyzed the methylation state of the T cell receptor beta chain gene (T beta) in monocyte and B cell DNA, focusing on the J1 and J2 regions of this gene in...

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Autori principali: Sakamoto, S, Young, H A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1988
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC338205/
https://ncbi.nlm.nih.gov/pubmed/2833728
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