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SECONDARY RECEPTOR EDITING IN THE GENERATION OF AUTOIMMUNITY
Receptor editing is the process that replaces the heavy chain or light chain variable region genes in a B-cell immunoglobulin receptor that is already productively rearranged. It is a major mechanism in the bone marrow for maintaining B-cell tolerance to autoantigens. We propose that a pathological...
Αποθηκεύτηκε σε:
| Κύριος συγγραφέας: | |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382035/ https://ncbi.nlm.nih.gov/pubmed/22349618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2012.02.004 |
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