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OnlineCall: fast online parameter estimation and base calling for illumina's next-generation sequencing

Motivation: Next-generation DNA sequencing platforms are becoming increasingly cost-effective and capable of providing enormous number of reads in a relatively short time. However, their accuracy and read lengths are still lagging behind those of conventional Sanger sequencing method. Performance of...

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Bibliographic Details
Main Authors: Das, Shreepriya, Vikalo, Haris
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381969/
https://ncbi.nlm.nih.gov/pubmed/22569177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts256
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