All human tRNATyr genes contain introns as a prerequisite for pseudouridine biosynthesis in the anticodon.
Two synthetic oligonucleotides, one specific for the 5' exon, the other spanning the splice junction, were used to show that (a) the human haploid genome contains at least 12 independent gene loci for tRNATyr, and (b) that all of them carry an intron. From one of the cloned human tRNATyr genes (pHtT...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1988
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3357766/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.5.1951 |
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