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Glucocorticoids relieve collectin-driven suppression of apoptotic cell uptake in murine alveolar macrophages through downregulation of SIRPα()
The lung environment actively inhibits apoptotic cell (AC) uptake by alveolar macrophages (AMø) via lung collectin signaling through signal regulatory protein α (SIRPα). Even brief glucocorticoid treatment during maturation of human blood monocyte-derived or murine bone marrow-derived macrophages (M...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381851/ https://ncbi.nlm.nih.gov/pubmed/22615206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200984 |
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