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Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics

Intestinal barrier dysfunction is a main feature of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Leak flux diarrhoea and a facilitated uptake of noxious antigens are the two consequences resulting from an impaired epithelial barrier. Barrier perturbations in IB...

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Bibliographic Details
Main Authors: Hering, Nina A, Fromm, Michael, Schulzke, Jörg-Dieter
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381811/
https://ncbi.nlm.nih.gov/pubmed/22219336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.224568
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