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Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics
Intestinal barrier dysfunction is a main feature of the inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis. Leak flux diarrhoea and a facilitated uptake of noxious antigens are the two consequences resulting from an impaired epithelial barrier. Barrier perturbations in IB...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Blackwell Science Inc
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381811/ https://ncbi.nlm.nih.gov/pubmed/22219336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.224568 |
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