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Subthreshold Desensitization of Human Basophils Re-capitulates the Loss of syk and FcεRI expression Characterized by Other Methods of Desensitization
BACKGROUND: Clinical desensitization of patients to drugs involves progressive exposure to escalating doses of drug over a period of 24 hours. In prior studies, this method was recapitulated in vitro to also demonstrate loss of mast cell or basophil responsiveness. However, most signaling studies of...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381337/ https://ncbi.nlm.nih.gov/pubmed/22702505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2012.04013.x |
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