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Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide

Although cell-based studies have shown that γ-tocotrienol (γTE) exhibits stronger anticancer activities than other forms of vitamin E including γ-tocopherol (γT), the molecular bases underlying γTE-exerted effects remains to be elucidated. Here we showed that γTE treatment promoted apoptosis, necros...

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Detalhes bibliográficos
Main Authors: Jiang, Qing, Rao, Xiayu, Kim, Choon Young, Freiser, Helene, Zhang, Qingbo, Jiang, Ziying, Li, Guilan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381336/
https://ncbi.nlm.nih.gov/pubmed/21400505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26054
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