Inhibition of p-Aminobenzoate and Folate Syntheses in Plants and Apicomplexan Parasites by Natural Product Rubreserine

Glutamine amidotransferase/aminodeoxychorismate synthase (GAT-ADCS) is a bifunctional enzyme involved in the synthesis of p-aminobenzoate, a central component part of folate cofactors. GAT-ADCS is found in eukaryotic organisms autonomous for folate biosynthesis, such as plants or parasites of the ph...

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Detalhes bibliográficos
Main Authors: Camara, Djeneb, Bisanz, Cordelia, Barette, Caroline, Van Daele, Jeroen, Human, Esmare, Barnard, Bernice, Van Der Straeten, Dominique, Stove, Christophe P., Lambert, Willy E., Douce, Roland, Maréchal, Eric, Birkholtz, Lyn-Marie, Cesbron-Delauw, Marie-France, Dumas, Renaud, Rébeillé, Fabrice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381196/
https://ncbi.nlm.nih.gov/pubmed/22577137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365833
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