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Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging

In this study, we demonstrate a method to quantify biomarker expression that uses an exogenous dual-reporter imaging approach to improve tumor signal detection. The uptake of two fluorophores, one nonspecific and one targeted to the epidermal growth factor receptor (EGFR), were imaged at 1 h in thre...

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Autori principali: Tichauer, Kenneth M., Samkoe, Kimberley S., Sexton, Kristian J., Gunn, Jason R., Hasan, Tayyaba, Pogue, Brian W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society of Photo-Optical Instrumentation Engineers 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381038/
https://ncbi.nlm.nih.gov/pubmed/22734757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.17.6.066001
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