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Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging
In this study, we demonstrate a method to quantify biomarker expression that uses an exogenous dual-reporter imaging approach to improve tumor signal detection. The uptake of two fluorophores, one nonspecific and one targeted to the epidermal growth factor receptor (EGFR), were imaged at 1 h in thre...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Society of Photo-Optical Instrumentation Engineers
2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381038/ https://ncbi.nlm.nih.gov/pubmed/22734757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.17.6.066001 |
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